Conference Program
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| Sunday, December 2, 2012 | |
| 12:30 | Registration |
| 14:30 - 14:45 | Welcome and introduction |
| Session I: Properties of RNA | |
| 14:45 - 15:15 |
Sarah Woodson, Johns Hopkins University, USA How RNA architecture encodes cooperativity of folding and RNP assembly [Inv.01] |
| 15:15 - 15:45 |
Anna Marie Pyle, Yale University, USA Structure and mechanism of group II introns: model systems for exploring the architecture of long noncoding RNAs [Inv.02] |
| 15:45 - 16:15 |
Ronald Breaker, Yale University, USA Prospects for Riboswitch Discovery and Analysis [Inv.03] |
| 16:15 - 16:45 | Refreshments |
| 16:45 - 17:15 |
Rachel Green, Johns Hopkins University, USA mRNA surveillance is driven by translation [Inv.04] |
| 17:15 - 17:45 |
Venki Ramakrishnan, MRC Laboratory of Molecular Biology, Cambridge, UK Dealing with defective or modified mRNA in translation [Inv.05] |
| 17:45 - 18:00 |
Short Talk: Silvia Rouskin, UCSF, USA (Jonathan Weissman’s Lab) Genome-wide measurement of RNA structure in vivo [O.1] |
| 18:00 - 19:00 | Drinks Reception |
| Monday, December 3, 2012 | |
| Session II: RNA machineries | 09:00 -09:30 | Fred Allain, ETH Zurich, Switzerland Novel modes of RNA recognition from the NMR structures of several RRM-RNA complexes [Inv.06] |
| 09:30 - 10:00 |
James Williamson, The Scripps Research Institute, USA Dynamics of Bacterial Ribosome Assembly in Cells [Inv.07] |
| 10:00 - 10:30 | Refreshments |
| 10:30 - 11:00 | Reinhard Lührmann, Max Planck Institute for Biophysical Chemistry, Germany Structure and regulation of the spliceosomal RNP remodeling enzyme Brr2 by Prp8 and links to retinitis pigmentosa [Inv.08] |
| 11:00 - 11:30 |
Juan Valcarcel, ICREA and Centre de Regulacio Genomica, Spain Functional networks of splicing regulation in cancer [Inv.09] |
| 11:30 - 11:45 | Short Talk: Jacob Schwartz, University of Colorado, USA (Tom Cech’s Lab) FUS binds noncoding RNAs and regulates Ser2 phosphorylation of the RNA polymerase II CTD [O.2] |
| 11:45 - 12:00 | Poster Teaser Session |
| 12:00 - 13:00 | Lunch Break |
| 13:00 - 15:00 | Poster Session I |
| Session III: Regulation of and by small RNAs | |
| 15:00 - 15:30 |
Witold Filipowicz, Friedrich Miescher Institute for Biomedical Research, Switzerland Mechanisms and regulation of microRNA repression in mammalian cells[Inv.10] |
| 15:30 - 16:00 | Narry Kim, Seoul National University, South Korea Regulation of MicroRNA [Inv.11] |
| 16:00 - 16:15 | Short Talk: Martin Bushell, University of Leicester, UK Functional requirement for eIF4AII in microRNA-mediated translational regulation [O.3] |
| 16:15 - 16:45 | Refreshments |
| 16:45 - 17:15 | Jörg Vogel, University of Würzburg, Germany New mechanisms of mRNA activation by small RNA [Inv.12] |
| 17:15 - 17: 45 |
Gisela Storz, National Institutes of Health, USA Additional levels of regulation provided by bacterial small RNAs [Inv.13] |
| 17:45 - 18:00 | Short Talk: Nadezda Tukhtubaeva, University of Vienna, Austria (Renee Schroeder’s Lab) RNA polymerase-binding elements attenuating transcription in E. coli [O.4] |
| 19:30 | Meet the Speakers Dinner |
| Tuesday, December 4, 2012 | |
| Session IV: RNAs and gene expression | |
| 08:45 - 09:15 | Marc Bühler, Friedrich Miescher Institute for Biomedical Research, Switzerland RNA-mediated eviction of a heterochromatin protein [Inv.14] |
| 09:15 - 09:30 | Short Talk: Ryuyu Fukunaga, University of Massachusetts Medical School, USA (Philip Zamore’s Lab) Dicer partner proteins tune the length, seed sequence, and targets of mature miRNAs [O.5] |
| 09:30 - 10:00 | Ben Blencowe, University of Toronto, Canada Function and evolution of alternatively spliced transcripts [Inv.15] |
| 10:00 - 10:30 | Refreshments |
| 10:30 - 11:00 | Bill Theurkauf, University of Massachusetts, USA Evolution of a transposon silencing machine [Inv.16] |
| 11:00 - 11:30 | Haru Siomi, Keio University, Japan Biogenesis of PIWI-interacting RNAs and transposon silencing in the Drosophila ovary [Inv.17] |
| 11:30 - 11:45 | Short Talk: Sara Macia, University of Edinburgh, UK (Javier Cáceres Lab) The Microprocessor controls the activity of mammalian LINE-1 retrotransposons [O.6] |
| 11:45 - 12:00 | Poster Teaser Session |
| 12:00 - 13:00 | Lunch Break |
| 13:00 - 15:00 | Poster Session II |
| Session V: RNAs in Development and Disease | |
| 15:00 - 15:30 | Phillip Sharp, Massachusetts Institute of Technology, USA Transcription of long noncoding RNAs and the functions of microRNAs in cancer [Inv.18] |
| 15:30 - 16:00 | Antonio Giraldez, Yale University, USA MicroRNAs, insights in the processing machinery and the mechanisms of regulation from zebrafish [Inv.19] |
| 16:00 - 16:30 | Refreshments |
| 16:30 - 17:00 | Peter Sarnow, Stanford University, USA Duals functions for microRNA 122: Masking the 5' end of hepatitis C viral RNA and regulating polyadenylation site usage in Insig1 [Inv.20] |
| 17:00 - 17:15 | Short talk: Sofia Francia, IFOM Foundation, Italy (Fabrizio d’Adda di Fagagna Lab) Site-specific DICER and DROSHA RNA products control the DNA damage response [O.7] |
| 17:15 - 18:15 | Q&A Discussion and Closing remarks |
